David A. Sinclair, A.O., Ph.D.
David A. Sinclair, A.O., Ph.D. is Professor of Genetics at Harvard Medical School, an Editor-in-Chief of the scientific journal Aging, and served as Founding Director of the Glenn Center for Biology of Aging Research at Harvard Medical School from 2004-2023.
Professor Sinclair’s pioneering work in genetics and aging biology has fundamentally shaped the world’s understanding of mechanisms of aging and age-related diseases. He is best known for his research on the molecular biology of aging, particularly the role of sirtuins, NAD+ metabolism, and epigenetic changes in regulating the aging process. In 2020, the Sinclair Lab reported successful use of cellular reprogramming to reverse, for the first time in any organism, age-related blindness.
Professor Sinclair has published over 180 peer-reviewed research articles that have been cited over 97,000 times, with an h-index of 114. He is the inventor on more than 50 patents and has co-founded over a dozen successful companies including MetroBiotech, EdenRoc Sciences, Fully Aligned Co, LLC, and Life Biosciences.
Professor Sinclair is the New York Times bestselling author of Lifespan: Why We Age-And Why We Don’t Have To and host of the Lifespan with Dr. David Sinclair podcast, which peaked as the #1 Health & Fitness show on Apple. Among over 25 career awards, Professor Sinclair has been recognized as one of TIME magazine’s 100 Most Influential People In The World for his scientific research and was appointed an Officer of the Order of Australia for distinguished service to humanity.
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