As psychedelics head toward mass adoption, two sides vie for control of their future. Investors have poured billions into the hope of safe, profitable, FDA-approved medicines, while decriminalization advocates are gaining ground in the fight for independent recreational, spiritual, and therapeutic use. In this panel, luminaries of the psychedelic world bring deep perspectives from their histories at the frontlines to explain the power struggle at the heart of the psychedelic renaissance and to paint a picture of how this clash will define our society's new relationship with drugs.