The coming years will see AI become full partners in our lives, going well beyond memo-writing aids to help us execute complex errands, make decisions and even fulfill our emotional needs. This presents thrilling possibilities, allowing us to live alongside an intelligence no humans have ever lived alongside before. It could also change us in incalculable ways. What happens to our brains when we no longer need to process information as we once did? What happens to our hearts when we no longer need other people to have meaningful relationships? What happens to us as humans when so much that has long defined that humanity -- the ability to independently think and feel -- is outsourced to machines? As we increasingly empower AI to act like a trusted spouse or deputy, join us for an ambitious conversation with the personalities imagining -- and hopefully safeguarding -- this head-spinning future.