Black Sherif began his career in 2019 with the release of his song "Cry for Me" on YouTube. His debut single "Money" was released on May 25, 2020, along with a music video. In May 2021, his single "First Sermon" was released, further increasing his audience. The song's sequel, "Second Sermon," was released in July and received a remix with fellow African artist Burna Boy.
Black Sherif breakthrough came in March 2022 with his single "Kwaku the Traveller," which reached Number 1 on the Ghanaian and Nigerian Apple Music charts and became his most popular song. He released his debut album, The Villain I Never Was, in October, supported by the singles "45" and "Soja".
Black Sherif has collaborated on songs with Stormzy, Burna Boy, Mabel, OdumoduBlvck, Smallgod and others.
Black Sherif performed at the 25th anniversary of the Music of Black Origin (MOBO) Awards, which took place at the OVO Arena in Wembley, London. In December 2022, he hosted his debut concert, the "Mozama Disco Concert," in Accra.
In 2023, he won BET International Flow at the BET Hiphop Awards hosted in Atlanta, USA.