Gangsta Boo was born and raised in Memphis, Tennessee. An anomaly within the generally misogynist late-'90s Dirty South rap scene, Gangsta Boo won substantial acclaim among audiences without sacrificing her pride. As the sole female %26 an original member of Memphis, TN, hardcore rap group Three 6 Mafia, she had held her own; it wasn't until her debut album, though, that she really started garnering an unprecedented amount of attention. Her first solo album, Enquiring Minds, was released in 1998 and reached number fifteen on the Billboard Top R%26B/Hip-Hop Albums chart and number 46 on the Billboard 200. Enquiring Minds found Gangsta Boo confronting the lyrical issues that hardcore female rappers such as Lil' Kim have to address: sexual politics, money hungry stereotypes, proving that a female can be hardcore, and so on. Enquiring Minds spawned the national anthem "Where Dem Dollas At!?" and helped to build the national stage for the Memphis music scene that was about to come.

After the success of Enquiring Minds, she played a critical role in the multi-platinum success of Three 6 Mafia's When the Smoke Clears: Sixty 6, Sixty 1 in 2000. She left the group following the release of their album When the Smoke Clears: Sixty 6, Sixty 1. Her 2001 album, Both Worlds *69, reached number eight on the R%26B/Hip-Hop chart and number 29 on the Billboard 200. It featured the hit singles "Love Don't Live (U Abandoned Me)" and "Can I Get Paid (Stripper's Anthem)."

Her third album, Enquiring Minds II: Soap Opera, released in 2003, peaked at number 53 on the R%26B/Hip-Hop chart and 24 on the Top Independent Albums chart. The album spawned the street hit "Sippin %26 Spinnin'" and the remix with Bun B has turned into a staple in her music catalog. Boo released the album under her new record label "Crazy Lady Entertainment." The album was also the first teaming of her and producer Drumma Boy whom have since created a musical bond. Gangsta Boo has also been collaborating with many artists in the rap industry over the past several years. She was featured on Lil Jon %26 The Eastside boy's 2004 multi-platinum smash "Crunk Juice" on the underground hit "Da Blow." She was featured on OutKast's 2000 album, "Stankonia." Ludacris' 2005 album "Disturbing The Peace." Pastor Troy's 2007 "Tool Muziq," plus countless others that you can find on Google. She also teamed up with Nick Scarfo for the Prophet Posse reunion and been featured on their last three albums, "The Return, Pt. 1," "The Return: Part 2 Belly of The Beast," and "Hood U.S.A."

She also has released several mixtapes over the past few years including, "Street Ringers: Volumes 1 %26 2," "Still Gangsta: The Memphis Queen Is Back," and "Gangsta Rock." Boo is currently in the studio putting the finishing touches on her 4th studio album titled "Forever Gangsta," which will hit stores in 2009.