Smart cities, autonomous driving as the norm, digital twins living in an ever-expanding metaverse, space industries booming and opening vast new opportunities and resources—these are all predictions for how our world will develop by 2050. It is an era where cyber-connectivity permeates every aspect of our infrastructure, to the point that there is no longer a functional distinction. During this panel, world-leading experts across industry, cyber defense, and the cyber investment landscape will share their unique insights on what is needed from a policy, innovation, industry, and protection (PIIP) standpoint to navigate a new normal and thrive in 2050.