Two of the most important recent innovations in mental health have been 1. the emergence of digital approaches and 2. the resurgence of scientific interest in the role of psychedelics. Also, these two approaches may have significant synergy. Because psychedelic treatment involves a limited dosing period that can have varying clinical outcomes, digital tools may be especially useful for tracking clinical responses to determine ongoing care. Second, evidence suggests that psychedelic treatment may create a window of brain plasticity when new learning can occur. Digital therapies could optimize this learning by helping to promote positive changes during this sensitive period. Our panel will explore these opportunities with experts in digital mental health and modern psychedelic science.