This presentation shines light on the currently popular relationship between Art and Science, and how this linkage is actualised through Technology. I address what is possible in this relationship and what is not, and how to work together with scientists from an artist’s point of view. As a starting point I use examples from my own artistic practice, specifically my latest piece ‘ANIMA’. This immersive interactive AI installation, which we call a ‘digital entity’, interprets body movements and sounds from observants, and communicates by expressing its emotional state through an emulated digital fluid on it’s spherical surface. In the process of constructing this installation I worked together with artificial intelligence researchers in order to create an intelligent interaction model.