Each episode is based on the contemporary problems of artificial intelligence be it the famous trolley problem, the ability of AI to think abstractly and act irrationally or intervene in private life if the purpose is good. Ultimately, "Alisa" boils down to the question if AI can be more human than man himself? And if so, is it good for humanity?

In the first episode "Driveress", Alice helps a young woman, Sasha, who works as a business-class taxi driver. Fed up with the passengers' biased attitude toward the woman behind the wheel, Sasha decides to order a very believable mustache... Alice is ready to support Sasha in her fight against prejudice but doubts such methods.