Henry is the primary caretaker for his chronically ill single mother Rebecca right up until the moment of her untimely death. With his girlfriend set to leave for college and his ascetic Jewish relatives ostensible strangers, Henry is left alone with a crippling grief, a burgeoning sense of guilt, as well as an unfinished bottle of Oxycontin 80s... The only person in his life that isn’t placating to his loss is his loud, subversive neighbour Ana, who has just moved in across the hall. As she tries to manage her own drug habit, as Henry begins to develop his own, the two of them form an unlikely friendship just as they become embroiled in a dangerous situation involving a missing bag of drugs.